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Antibacterial Properties and Efficacy of LL-37 Fragment GF-17D3 and Scolopendin A2 Peptides Against Resistant Clinical Strains of Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii In Vitro and In Vivo Model Studies.
Farzi N, Oloomi M, Bahramali G, Siadat SD, Bouzari S. Farzi N, et al. Probiotics Antimicrob Proteins. 2023 May 6. doi: 10.1007/s12602-023-10070-w. Online ahead of print. Probiotics Antimicrob Proteins. 2023. PMID: 37148452
Isolates harbored complete resistance toward the majority of antibiotics and MIC values ranged between 1 and > 512 g/ml. The majority of isolates exhibited strong biofilm activity. ...Scolopendin A2 was found to have antibacterial efficacy against P. aeruginosa, S. aure …
Isolates harbored complete resistance toward the majority of antibiotics and MIC values ranged between 1 and > 512 g/ml. The major …
MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy.
Marofi F, Alexandrovna KI, Margiana R, Bahramali M, Suksatan W, Abdelbasset WK, Chupradit S, Nasimi M, Maashi MS. Marofi F, et al. Stem Cell Res Ther. 2021 Dec 4;12(1):597. doi: 10.1186/s13287-021-02662-6. Stem Cell Res Ther. 2021. PMID: 34863308 Free PMC article. Review.
The MSCs-derived exosomes comprise molecular components including lipid, proteins, DNA, microRNA, and also mRNA, which target molecular pathways and also biological activities in recipient cells (e.g., endothelial cell, keratinocyte, and fibroblast). The secreted exosome m …
The MSCs-derived exosomes comprise molecular components including lipid, proteins, DNA, microRNA, and also mRNA, which target molecular path …
RNA Expression Analysis of Mycobacterial Methyltransferases Genes in Different Resistant Strains of Mycobacterium tuberculosis.
Tarashi S, Zamani MS, Bahramali G, Fuso A, Vaziri F, Karimipoor M, Fateh A, Siadat SD. Tarashi S, et al. Iran Biomed J. 2022 May 1;26(3):240-51. doi: 10.52547/ibj.26.3.240. Iran Biomed J. 2022. PMID: 35216515 Free PMC article.
RESULTS: Only two mutations were found in isoniazid resistance (INHR) strain for Rv3919c (T to G in codon 341) and Rv1392 (G to A in codon 97) genes. Overexpression of Rv0645c, Rv2756c, Rv3263, and Rv2966c was detected in all sensitive and resistant isolates. ...
RESULTS: Only two mutations were found in isoniazid resistance (INHR) strain for Rv3919c (T to G in codon 341) and Rv1392 (G t …
Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder.
Nouraei H, Firouzabadi N, Mandegary A, Zomorrodian K, Bahramali E, Shayesteh MRH, Ansari S. Nouraei H, et al. J Neuropsychiatry Clin Neurosci. 2018 Winter;30(1):45-50. doi: 10.1176/appi.neuropsych.16120322. Epub 2017 Jun 23. J Neuropsychiatry Clin Neurosci. 2018. PMID: 28641498
Regarding rs41423247 polymorphism, carriers of the CG and GG genotype responded significantly better to fluoxetine compared with CC carriers (p=0.008, OR=3.3, 95% CI=1.35-8.07). Moreover, the G allele of rs41423247 polymorphism was strongly associated with response to fluo …
Regarding rs41423247 polymorphism, carriers of the CG and GG genotype responded significantly better to fluoxetine compared with CC carriers …
Genetic Variants of Angiotensin-Converting Enzyme Are Linked to Autism: A Case-Control Study.
Firouzabadi N, Ghazanfari N, Alavi Shoushtari A, Erfani N, Fathi F, Bazrafkan M, Bahramali E. Firouzabadi N, et al. PLoS One. 2016 Apr 15;11(4):e0153667. doi: 10.1371/journal.pone.0153667. eCollection 2016. PLoS One. 2016. PMID: 27082637 Free PMC article.
RESULTS: There were strong associations between both DD genotype of ACE I/D and the D allele, with autism (P = 0.006, OR = 2.9, 95% CI = 1.64-5.13 and P = 0.006, OR = 2.18, 95% CI = 1.37-3.48 respectively). Furthermore, a significant association between the G allele of rs4 …
RESULTS: There were strong associations between both DD genotype of ACE I/D and the D allele, with autism (P = 0.006, OR = 2.9, 95% CI = 1.6 …
Beta Adrenoceptor Polymorphism and Clinical Response to Sertraline in Major Depressive Patients.
Firouzabadi N, Raeesi R, Zomorrodian K, Bahramali E, Yavarian I. Firouzabadi N, et al. J Pharm Pharm Sci. 2017;20:1-7. doi: 10.18433/J3W31F. J Pharm Pharm Sci. 2017. PMID: 28459660 Free article.
Moreover, carriers of C allele responded three times more to sertraline than patients with the G allele (P=0.001; OR= 3.3; 95%CI= 1.72-6.50). CONCLUSION: In conclusion, our results support the hypothesis that genetic variation of beta1AR might influence clinical response t …
Moreover, carriers of C allele responded three times more to sertraline than patients with the G allele (P=0.001; OR= 3.3; 95%CI= 1.7 …
Venom Components of Iranian Scorpion Hemiscorpius lepturus Inhibit the Growth and Replication of Human Immunodeficiency Virus 1 (HIV-1).
Zabihollahi R, Pooshang Bagheri K, Keshavarz Z, Motevalli F, Bahramali G, Siadat SD, Momen SB, Shahbazzadeh D, Aghasadeghi MR. Zabihollahi R, et al. Iran Biomed J. 2016 Nov;20(5):259-65. doi: 10.22045/ibj.2016.02. Epub 2016 Sep 4. Iran Biomed J. 2016. PMID: 27594443 Free PMC article.
RESULTS: The H. lepturus crude venom inhibited HIV replication by 73% at the concentration of 200 g/ml, while it did not show significant anti-HSV activity. It also inhibited the cell-free viral particles in a virucidal assay, while it showed no toxicity for the target cel …
RESULTS: The H. lepturus crude venom inhibited HIV replication by 73% at the concentration of 200 g/ml, while it did not show signifi …